Mortality in COPD: Inevitable or Preventable? Insights from the Cardiovascular Arena

Medical Malpractice: A Preventable or Inevitable Issue

The epidemiology and economics of chronic obstructive pulmonary disease.

Chronic obstructive pulmonary disease (COPD) is a preventable and treatable disease responsible for a large human and economic burden around the world. Cigarette smoking is the main risk factor for COPD in the developed world, although other important risk factors include occupational exposures, air pollution, airway hyperresponsiveness, asthma, and genetic predisposition. In most of the world,...

The Use of Population Attributable Risk to Estimate The Impact of Preventive Interventions of Smoking Cessation in Chronic Obstructive Pulmonary Disease(COPD)

Chronic pulmonary disorders are a set of diseases that restrict respiration airflow(1).Most of these diseases are chronic obstructive pulmonary disease (COPD)(1). According to the WHO  report, mortality from COPD is increasing worldwide. It is expected to be the third leading cause of death worldwide by 2030(2) (the sixth leading cause of death in 1990(3). This disease causes significant costs ...

Insights into role of microRNAs in cardiac development, cardiac diseases, and developing novel therapies

Objective(s): MicroRNAs (miRNAs) are a subfamily of small noncoding RNAs that play a variety of roles in regulating gene expression in nearly all organisms. They affect different biological pathways by post-transcriptionally regulating mRNAs. Aside from miRNAs’  role in maintaining cellular homeostasis, their perturbation is related to several pathologic states and dis...

Evaluation of Prognostic Factors of Mortality in Patients with Chronic Obstructive Pulmonary Disease

Background and Objective: Chronic Obstructive Pulmonary Disease (COPD) is a chronic obstructive and irreversible disease which has a high mortality and morbidity rate. Systemic inflammation and the thrombotic process can influence the prognosis of these patients. The objectives of this study were to evaluate prognostic effects of CBC indices (WBC, PMN, MPV, RDW), forced expiratory volume-one se...